FLUCONAZOLE FAILURE IN THE TREATMENT OF COCCIDIOIDAL MENINGITIS

Fluconazole Failure in the Treatment of Coccidioidal Meningitis

Introduction: Coccidioidal meningitis (CM) is the most lethal form of disseminated coccidioidomycosis.Current guidelines recommend fluconazole as initial therapy but there has been a paucity of data regarding failure of fluconazole and optimal fluconazole dosage in the treatment of CM.We conducted this study to understand risk factors for fluconazo

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Neural basis of corruption in power-holders

Corruption often involves bribery, when a briber suborns a power-holder to gain advantages usually at a cost of moral transgression.Despite its wide presence in human societies, the neurocomputational basis of bribery remains elusive.Here, using model-based fMRI, we investigated the neural substrates of how a power-holder decides to accept or rejec

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Responsive Plasmonic Nanomaterials for Advanced Cancer Diagnostics

Plasmonic nanostructures, particularly of noble-metal Au and Ag, have attracted long-lasting research interests because of their intriguing physical and chemical properties.Under light excitation, their conduction operation igloo white electrons can form collective oscillation with the electromagnetic fields at particular wavelength, leading to loc

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